Categories
sugardaddyforme-inceleme visitors

dos.dos Neural Signaling Systems and you may Gender Transform

dos.dos Neural Signaling Systems and you may Gender Transform

How might estrogen synthesis through aromatase activity be regulated in sex changing species? Relatively little information is available, but findings from gonochoristic fishes and other vertebrates suggest some intriguing possibilities. The promoter region of brain aromatase genes in the bi-directionally sex-changing gobies G. histrio and T. okinawae have estrogen response elements (ERE), but an ERE was suggested only for gonadal aromatase in T. okinawae [44, 85,86]. Estrogen responsiveness mediated transcriptionally through an ERE could help explain E2 effects on the occurrence or prevention of sex change if exogenous estrogen maintained or induced aromatase expression in brain or gonad. Consistent with this estrogenic regulation of neural aromatase expression, female bluehead wrasses receiving E2 implants do show higher sugardaddyforme uygulaması nedir brain aromatase mRNA abundances than controls (Hunkin et al., in preparation). Kobayashi and colleagues also described cAMP response elements (CRE) in the promoter regions of both forms of aromatase, consistent with results from zebrafish. By contrast, Gardner did not describe CREs for either aromatase in G. histrio, but did suggest a glucocorticoid response element (GRE) in the gonadal aromatase gene (although a GRE was not found in two other sex changers examined). The somewhat conflicting results from different studies are difficult to reconcile, but efforts to sequence the genome from a representative of every vertebrate genus (genome10K.org) could provide data allowing characterization of aromatase promoters across fish species within a few years.